Laboratory of Cytobiochemistry

The scope and methodology of the research is concerned with yeast from the genera Malassezia, Candida and Saccharomycesas as well as different cancer cell lines. We conduct analysis of lipid composition, protein comparison and cell viability in different object of our research.

• Mechanisms of functioning and regulation of key enzymes isolated from animal tissues and yeast.
• Studies of enzymes derived from the tissues of various animal species in the aspect of adapting their metabolism to environmental conditions.
• Research on protein and lipid profile of genetic related yeasts.
• Comparisons of effects of vit. B1 derivatives and mechanisms of their action in different opportunistic yeast cells (Malassezia, Candida) as well as cancer cells.
• Analysis of lipid and protein composition, of various strains of opportunistic yeast.

• Determination of mechanisms of synergistic action of oxitiamine and ketaconazol against opportunistic yeast Malassezia pachydermatis, 1st competition of the National Science Center for financing research projects. NCN, Miniature, project leader: dr Magdalena Siemieniuk, duration: 2017 – 2018.
• Characteristic of protein profiles of Malasssezia pachydermatis in the diagnostic aspect using twodimensional electrophoresis, NCN, Preludium, project leader: dr Urszula Czyżewska duration: 2014-2017.

• Department of Pharmaceutical Technology, The Faculty of Pharmacy, Medical University of Bialystok, Poland
• Laboratory of cell signalling and metabolic disorders, Nencki Institute of experimental biology, Polish Academy of Sciences, Warsaw, Poland
• Laboratory of molecular medical biochemistry, Nencki Institute of experimental biology, Polish Academy of Sciences, Warsaw, Poland
• Department of Cellular Signal Transduction, Mossakowski Medical Research Centre Polish Academy of Sciences, Warsaw, Poland
• Department of Preclinical Sciences, Faculty of Veterinary Medicine, Warsaw University of Life Sciences, Warsaw, Poland
• Department of Veterinary Mikrobiology, Institute of Biological Bases of Animal Diseases, University of Life Sciences, Lublin, Poland
• Department of Comparative Biochemistry and Bioanalytics, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Cracow, Poland
• GIGA Neurosciences, University of Liege, Liege, Belgium

• 7890B Gas Chromatograph (GC) System, Muse Cell Analyzer, UV-VIS Jasco V-730 speatrophotometer, equipment for cell cultures and basic biochemical analysis